The inflammatory response which occurs during the healing process that we promote also activates what are known as “M2 Macrophages”. Macrophages are white blood cells which engulf and digest cellular debris, foreign substances, microbes, cancer cells, and indeed anything else without proteins that are good for healthy cells. M2 macrophages decrease the inflammation we cause and encourage tissue regeneration and repair. We also stimulate the migration of basal keratinocytes up to the surface of the skin. Wounds to the skin are repaired, in part, by the migration of keratinocytes from the basal layer of the skin which then fill-in the gaps created by the micro-wounds we create. Within the healed epidermis they are, in turn, replaced by keratinocytes that originate from the epidermis.